The sites participating in eMERGE and the eMERGE-PGx project include:
- Children's Hospital of Pennsylvania
- Cincinnati Children's Medical Center with Boston Children's Hospital
- Essentia Rural Health with Marshfield Clinic and The Pennsylvania State University
- Geisinger Health System
- Group Health Cooperative with University of Washington
- Mayo Clinic
- Mount Sinai School of Medicine
- Northwestern University
- Vanderbilt University
SPHINX is a web-based tool for exploring drug response implications of genetic variation across the eMERGE PGx project cohort.
The eMERGE-PGx project is a multi-center pilot of pharmacogenetic sequencing in clinical practice. Once fully enrolled, SPHINX will contain data on nearly 9000 subjects from participating electronic medical record (EMR) systems. PGRN-Seq sequencing will identify common variants, some with known clinical implications, and also variants of unknown significance. SPHINX has a public-facing gene variant repository that provides variant summary data.